Polypid Ltd.
Clinical trials sponsored by Polypid Ltd., explained in plain language.
Biopharma developing controlled-release drug delivery systems for surgical infections.
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New gel could slash infection risk after abdominal surgery
Prevention CompletedThis study tests whether a gel called D-PLEX, which slowly releases the antibiotic doxycycline, can prevent surgical site infections in people undergoing colorectal or abdominal surgery. About 975 participants will receive either D-PLEX plus standard care or standard care alone. …
Phase: PHASE3 • Sponsor: PolyPid Ltd. • Aim: Prevention
Last updated Jul 15, 2026 00:00 UTC
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New antibiotic gel aims to stop surgical infections in their tracks
Prevention CompletedThis large Phase 3 trial tested a new antibiotic gel called D-PLEX, which is placed into the surgical wound during abdominal surgery to slowly release the antibiotic doxycycline over time. The goal was to see if it could prevent surgical site infections better than standard care …
Phase: PHASE3 • Sponsor: PolyPid Ltd. • Aim: Prevention
Last updated Jun 27, 2026 12:23 UTC
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New gel wipes out infections after heart surgery in early trial
Prevention CompletedThis study tested a new treatment called D-PLEX to prevent serious wound infections after heart surgery. 81 adults, including those at high risk, received either D-PLEX plus standard care or standard care alone. Over 90 days, no one who got D-PLEX developed a sternal infection, w…
Phase: PHASE1, PHASE2 • Sponsor: PolyPid Ltd. • Aim: Prevention
Last updated Jun 27, 2026 12:06 UTC
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New gel could slash infection risk after colon surgery
Prevention CompletedThis study tested a gel called D-PLEX, applied directly to the surgical wound during abdominal surgery, to see if it could prevent infections. Half of the 202 participants received the gel plus standard care, and the other half received standard care alone. The main goal was to m…
Phase: PHASE2 • Sponsor: PolyPid Ltd. • Aim: Prevention
Last updated Jun 27, 2026 12:00 UTC