Peking University Shenzhen Hospital

This study is testing a drug called iruplinalkib in people with advanced ALK-positive lung cancer who have already tried and stopped responding to lorlatinib. Researchers want to see if iruplinalkib can help control the cancer and how safe it is. About 20 adults will take part, a…

This early-phase study tests a new treatment called CAR-DC for people with advanced solid tumors (cancers that have spread). The therapy uses a patient's own immune cells, modified in a lab to recognize and attack cancer cells that have certain markers. The main goals are to chec…

This study tests a new brain-wave monitor (MGRNOX) to guide painkiller use during gallbladder surgery. 112 adults will either get standard anesthesia or MGRNOX-guided care. The goal is to see if the monitor helps doctors use fewer opioids while still controlling pain.

This study tests whether giving a combination of two medicines (esketamine and dexmedetomidine) during hip fracture surgery can improve sleep quality afterward in patients aged 65 and older. Half of the 96 participants will receive the drug combo, and the other half will receive …

This study looks at 101 adults having thyroid surgery to find the exact amount of the anesthetic ciprofol needed to reach a moderate sedation level. It also checks how well brain-wave monitoring matches sedation depth. After surgery, patients are followed for pain and mental clar…

This study aims to find the right dose of remifentanil (a strong painkiller) to prevent sudden changes in heart rate and blood pressure when a breathing tube is placed during anesthesia. About 99 adults having planned surgery will take part. Researchers will compare two drug comb…