Pediatric Brain Tumor Consortium
Clinical trials sponsored by Pediatric Brain Tumor Consortium, explained in plain language.
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Experimental antibody APX005M takes on childhood brain cancers
Disease control CompletedThis early-stage trial is testing an experimental drug called APX005M in 32 children with brain tumors that have come back or are hard to treat, including a type of brain stem glioma. The drug works by activating the immune system to attack cancer cells. The main goals are to fin…
Phase: PHASE1 • Sponsor: Pediatric Brain Tumor Consortium • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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New drug shows promise in early trial for kids with deadly brain cancer
Disease control CompletedThis early-phase study tested an experimental drug called INCB7839 in 13 children whose high-grade gliomas (aggressive brain tumors) had come back or worsened after standard treatment. The main goals were to find a safe dose and check for side effects. The drug works by blocking …
Phase: PHASE1 • Sponsor: Pediatric Brain Tumor Consortium • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC