Otsuka Pharmaceutical Co., Ltd.

This study looked at whether taking a new once-weekly form of the schizophrenia drug brexpiprazole with food changes how the body absorbs it. Fifty-nine adults with stable schizophrenia took the drug once with food and once without, and researchers measured drug levels in their b…

This study tested an experimental drug called OPC-131461 in 157 adults with heart failure who still had swelling (edema) despite taking standard water pills. The goal was to see if the drug could help reduce body weight by removing extra fluid. Participants received either a plac…

This study looked at 1802 people in Japan with autosomal dominant polycystic kidney disease (ADPKD) who were taking the drug tolvaptan. Researchers wanted to see how safe and effective the drug is in real-world settings, not just in controlled trials. They measured kidney growth …

This study tested a daily pill called ETC-1002 in 130 adults with very high LDL ("bad") cholesterol who could not take statins or did not get enough help from them. The goal was to see if the drug is safe and lowers cholesterol over 52 weeks. Results showed the drug reduced LDL c…

This early-stage study tested a new drug (OPB-111077) added to two standard chemotherapy drugs (bendamustine and rituximab) in 36 adults with a type of blood cancer called diffuse large B-cell lymphoma that had returned or stopped responding to treatment. The main goal was to see…