Otsuka Pharmaceutical Co., Ltd.

This early-phase trial tested an experimental drug called OPB-111077 combined with two standard chemotherapy drugs (bendamustine and rituximab) in 36 people whose diffuse large B-cell lymphoma had come back or stopped responding to treatment. The main goal was to check the safety…

This study tested a daily pill called ETC-1002 in 130 adults with very high LDL ("bad") cholesterol who either didn't respond well to statins or had side effects from them. Over 52 weeks, researchers checked how safe the drug was and how much it lowered cholesterol. The goal was …

This study looked at whether taking a new once-weekly schizophrenia medication with food changes how much of the drug gets into the blood. Fifty-nine adults with stable schizophrenia took the drug once with food and once without food. The goal was to see if food affects drug leve…

This study followed 1802 Japanese patients with autosomal dominant polycystic kidney disease (ADPKD) who were taking tolvaptan in real-world clinics. Researchers tracked safety and how well the drug slowed kidney growth. The goal was to see if tolvaptan works as well outside cont…

This study tested an experimental drug called OPC-131461 in 157 people with congestive heart failure who still had fluid buildup despite taking standard water pills. Participants received different doses of the drug or a placebo daily for 14 days. The main goal was to see if the …