National Center For Complementary And Integrative Health (nccih)

This study aims to understand how psychological factors, such as expectations and emotions, influence the way we perceive pain. Healthy volunteers aged 18-50 will undergo brain scans (MRI) and pain tests (heat or electric shocks) while their heart rate, breathing, and other respo…

This study aims to better understand pain by testing how people with and without pain disorders respond to different sensations like heat, cold, and pressure. Researchers will also use questionnaires, medical history, and brain scans to gather information. The goal is to learn mo…

This study tests if mild electrical stimulation of the left ear can change how healthy adults perceive pain. Researchers will compare stimulating the vagus nerve area versus a non-nerve area. Participants will rate pain from heat on their arm and complete mood questionnaires. The…

This study aims to understand the different types of fatigue people experience, especially those with conditions like cancer, lupus, and chronic fatigue syndrome. Researchers will compare fatigued and non-fatigued adults using interviews, questionnaires, physical tests, and optio…

This study looks at how nerves send signals in people with PIEZO2 Deficiency Syndrome (PDS), a rare genetic condition that reduces the ability to feel touch and pain. Researchers will use tiny needles to record nerve activity while applying gentle sensations like brushing, heat, …

This study looks at how a person's background—like race or ethnicity—affects how they feel and show pain, and how others judge that pain. Researchers will measure pain responses in healthy volunteers and then test if people can learn to assess pain more accurately. The goal is to…