National Cancer Institute, Naples

This study tests whether using artificial intelligence to guide IV fluids during major cancer surgery can prevent dangerous drops in blood pressure. About 176 adults having long cancer surgeries will either get AI-guided fluid management or standard care. The goal is to see if th…

This study tests a drug called Inavolisib in about 48 women with advanced endometrial cancer that has a specific genetic change (PIK3CA mutation). The goal is to see if the drug can shrink tumors or slow cancer growth. Participants must have tried other treatments first and have …

This study tests whether adding a balanced cannabis extract (THC/CBD) to standard pain treatment can reduce symptom burden in 156 adults with advanced solid tumors. Participants will receive either the cannabis extract or a placebo for 8 weeks. The goal is to see if it improves o…

This study looks at how well a special type of surgery works for people with advanced gynecologic cancers that have spread to major blood vessels. The surgery removes both the cancer and the affected blood vessel part, sometimes rebuilding the vessel. Researchers will track 130 p…