Cannabis oil trial aims to ease cancer Patients' daily suffering

NCT ID NCT07459920

Not yet recruiting Symptom relief Sponsor: National Cancer Institute, Naples Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a cannabis extract oil containing THC and CBD can reduce the overall symptom burden in people with advanced solid tumors who are already taking strong painkillers. About 156 participants will receive either the cannabis oil or a placebo for 8 weeks. The main goal is to see if the cannabis oil improves total symptom scores, including pain, nausea, and fatigue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabis extract oil (10 mg/ml THC and 10 mg/ml CBD)
What this could lead to: If it works, this could offer a new way to reduce multiple symptoms like pain, nausea, and poor appetite in advanced cancer patients.
What could go wrong: This is a phase 2 trial with only 156 people, so results are preliminary. The cannabis extract may cause side effects like dizziness or drowsiness, and it might not improve symptoms more than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED MALIGNANT SOLID TUMOR

Contacts and locations

Locations

IRCCS Fondazione G. Pascale

Naples, Italy

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