Mineralys Therapeutics Inc.

This phase 2 trial tested whether adding the experimental drug lorundrostat to standard SGLT2 inhibitor therapy can lower blood pressure in adults with chronic kidney disease and albuminuria (protein in urine). Sixty participants received either lorundrostat or a placebo for four…

This Phase 3 trial tested a new drug called lorundrostat in over 1,000 adults whose high blood pressure remained uncontrolled despite taking 2 to 5 other medications. Participants received either lorundrostat or a placebo daily for 12 weeks. The main goal was to see if the drug l…

This study tested an experimental drug called lorundrostat in 285 adults whose high blood pressure remained uncontrolled despite taking 2 to 5 other medications. The drug works by blocking a hormone that raises blood pressure. Researchers measured how much it lowered blood pressu…

This phase 2 trial tested a drug called lorundrostat in 48 adults with moderate-to-severe obstructive sleep apnea and high blood pressure. Participants took either the drug or a placebo for four weeks to see if it improved breathing during sleep and lowered blood pressure. The st…