Melanoma And Skin Cancer Trials Limited

This study tests whether the immunotherapy drug avelumab can help prevent Merkel cell carcinoma, a rare skin cancer, from returning after initial treatment. About 122 adults with stage I to III Merkel cell carcinoma will receive either avelumab or a placebo. The main goal is to s…

This study tests whether adding radiation therapy (either external beam or a targeted radioactive drug called Lutathera) to the immunotherapy avelumab can help control metastatic Merkel cell carcinoma. About 19 adults with advanced disease will receive avelumab every two weeks fo…

This phase 3 trial tests whether a cream containing sirolimus (rapamycin) can prevent facial skin cancers in people who have received an organ transplant. 146 participants apply the cream or a placebo to their face every night for 6 months. The study counts new skin cancers durin…