Melanoma And Skin Cancer Trials Limited

This study tests whether combining the immunotherapy drug avelumab with two types of radiation therapy can help control metastatic Merkel cell carcinoma, a rare and aggressive skin cancer. About 19 adults with advanced disease that has spread will receive the combination treatmen…

This study tests a cream containing sirolimus, applied nightly for 24 weeks, to prevent skin cancer on the face of organ transplant recipients. 146 adults who have had an organ transplant and a past skin cancer are participating. The cream is compared to a placebo to see if it re…

This study tests whether the immunotherapy drug avelumab can help prevent Merkel cell carcinoma from returning after initial treatment. About 122 adults with stage I to III Merkel cell carcinoma are randomly assigned to receive either avelumab or a placebo. The main goal is to se…