Immunotherapy drug avelumab aims to stop merkel cell cancer recurrence in early-stage patients
NCT ID NCT04291885
First seen Apr 12, 2026 · Last updated May 05, 2026 · Updated 2 times
Summary
This study tests whether the immunotherapy drug avelumab can help prevent Merkel cell carcinoma from returning after initial treatment. About 122 adults with stage I to III Merkel cell carcinoma are randomly assigned to receive either avelumab or a placebo. The main goal is to see if avelumab improves recurrence-free survival over about 3.5 years of follow-up.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alfred Hospital
Melbourne, Victoria, 3000, Australia
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Auckland City Hospital
Auckland, New Zealand
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Cairns Hospital
Cairns, Queensland, 4870, Australia
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Calvary Mater Hospital
Sydney, New South Wales, 2298, Australia
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Cancer Care Service, Bundaberg Base Hospital
Bundaberg, Queensland, 4670, Australia
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Cancer Care Service, Hervey Bay Hospital
Hervey Bay, Queensland, 4655, Australia
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Cancer Care Wollongong
Wollongong, New South Wales, 2500, Australia
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Chris O'Brien Lifehouse
Sydney, New South Wales, 2050, Australia
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Icon Cancer Centre Hobart
Hobart, Tasmania, 7000, Australia
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Mackay Hospital and Health Service
Mackay, Queensland, 4740, Australia
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Melanoma Institute Australia
Sydney, New South Wales, 2065, Australia
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Peter MacCallum Cancer Centre
Melbourne, Victoria, 3000, Australia
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Port Macquarie Base Hospital
Port Macquarie, New South Wales, 2444, Australia
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Princess Alexandra Hospital
Woolloongabba, Queensland, 4102, Australia
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Royal Adelaide Hospital
Adelaide, South Australia, 5000, Australia
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Royal Brisbane and Woman's Hospital
Brisbane, Queensland, 4029, Australia
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Royal North Shore Hospital
Sydney, New South Wales, 2065, Australia
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Tasman Health Care
Southport, Queensland, 4215, Australia
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Townsville Hospital
Townsville, Queensland, Australia
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Westmead Hospital
Sydney, New South Wales, 2145, Australia
Conditions
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