Medtronic Cardiovascular

This study tests whether a second minimally invasive valve replacement (redo TAVR) is safe and effective for people whose first artificial aortic valve has failed. About 225 participants will receive either a Medtronic or Edwards replacement valve. The goal is to see if the new v…

This study is tracking 80 people with severe pulmonary valve regurgitation (a leaky heart valve) who receive the Harmony Transcatheter Pulmonary Valve. The valve is placed through a catheter, avoiding open-heart surgery. Researchers will check if the valve works well and stays in…

This study compares two medical devices (Endurant and Excluder stent grafts) used to treat abdominal aortic aneurysms—a bulging blood vessel in the belly that can be life-threatening if it bursts. About 600 people with large aneurysms will be randomly assigned to get one of the t…

This study tests a new device that replaces a leaky tricuspid heart valve using a thin tube inserted through a leg vein, avoiding open-heart surgery. It includes 150 people with severe tricuspid regurgitation who are too high-risk for surgery. The goal is to see if the device is …

This study tests a new device (Intrepid TMVR) to replace the mitral valve in people with severe mitral regurgitation (leaky heart valve) who are not candidates for standard surgery or repair. About 400 participants will receive the device and be followed for safety and effectiven…

This study tests a new device to replace the mitral valve in people with severe mitral regurgitation (a leaky heart valve) who cannot have standard surgery or a less invasive repair. About 1,056 participants will receive the device and be followed for safety and quality of life. …