Institut Paoli-calmettes
Clinical trials sponsored by Institut Paoli-calmettes, explained in plain language.
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New hope for aggressive breast cancer: adding immunotherapy to standard treatment
Disease control OngoingThis study is testing whether adding the immunotherapy drug pembrolizumab to standard chemotherapy before surgery helps eliminate aggressive inflammatory breast cancer tumors. It involves 52 adults with a specific type of breast cancer (HER2-negative) that has not spread. The mai…
Phase: PHASE2 • Sponsor: Institut Paoli-Calmettes • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Scientists search for clues in breast Cancer's resistance to treatment
Knowledge-focused OngoingThis study aims to understand why some advanced breast cancers respond well to standard hormone therapy while others become resistant. Researchers will analyze tumor samples from 115 patients before and after treatment to identify genetic markers that predict treatment success. T…
Phase: NA • Sponsor: Institut Paoli-Calmettes • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists search for hidden cancer clues in tissue samples
Knowledge-focused OngoingThis study aims to identify molecular patterns in tissue samples that might predict how gynecological cancers behave. Researchers will collect samples from 300 women with suspected ovarian, cervical, or endometrial cancer. The goal is to link these molecular findings to the patie…
Phase: NA • Sponsor: Institut Paoli-Calmettes • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:40 UTC
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Blood test could predict which kidney cancer drugs work best
Knowledge-focused OngoingThis study aims to determine if measuring two specific proteins (MMP2 and MMP9) in blood can help predict how well patients with metastatic kidney cancer will respond to anti-angiogenic drugs like Sunitinib or Pazopanib. Researchers will compare protein levels in 50 patients rece…
Phase: NA • Sponsor: Institut Paoli-Calmettes • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC