Institut Bergonié

This phase 2 trial tests whether adding the immunotherapy drug retifanlimab to standard chemotherapy before surgery can improve outcomes for people with resectable soft-tissue sarcoma. About 66 participants will receive either chemotherapy alone or chemotherapy plus retifanlimab.…

This study was designed to test a combination of chemotherapy drugs (cisplatin and docetaxel) with radiation therapy for people with advanced non-small cell lung cancer that could not be removed by surgery. The plan included chemotherapy before, during, and after radiation. Howev…

This study was designed to test a combination of two drugs, Ezabenlimab and BI907828, in people with advanced solid tumors like sarcoma, lung cancer, and breast cancer. The goal was to see if the treatment could control the disease for at least 24 weeks. However, the trial was wi…

This study looks at whether a special biopsy done with ultrasound guidance before surgery can correctly tell if a uterine tumor is cancerous or not. It involves 19 women aged 35 and older who have suspicious uterine tumors. The goal is to avoid risky surgical procedures if the tu…

This study tests whether using a special monitor (ANI) during ovarian cancer surgery to guide pain medicine can lower the chance of chronic pain three months after the operation. About 126 women having open surgery for ovarian cancer will be randomly assigned to standard care or …

This study aimed to see if offering aesthetic care (like makeup and skincare) to women who had a mastectomy or lumpectomy for breast cancer could improve their body image and quality of life. It planned to compare women who received these sessions with those who did not. However,…

This study tests a new way of organizing care for people aged 70 and older who have cancer (breast, lung, colorectal, or prostate) plus at least one other serious health condition. The GERONTE program brings all their doctors and nurses together using a shared digital care plan. …

This study follows 430 people with Cowden's disease (a PTEN gene mutation) to better understand their risk of developing cancer. Researchers will track how many participants get cancer over time. The goal is to improve monitoring and care for this high-risk group.

This pilot study tests whether elderly cancer patients (65 and older) can use an online tool to regularly report symptoms and quality of life during treatment. Over 3 months, patients fill out weekly questionnaires on side effects and two longer surveys on well-being. The goal is…

This study looks at how surgery for soft tissue sarcoma in the leg affects the daily function of patients aged 70 and older. Researchers will use questionnaires to measure quality of life and physical ability before and after treatment. The goal is to identify factors that help p…

This study checks for muscle loss (sarcopenia) in 25 women with advanced ovarian cancer before they start chemotherapy. Using CT scans, researchers want to see how common this condition is and if it affects treatment timing. The goal is to better understand how muscle health rela…

This study brings together cancer experts to agree on standard definitions for key measurements used in cancer clinical trials, such as how long patients live without their cancer getting worse. Currently, different trials define these measurements in different ways, making it ha…

This study planned to test whether MRI-guided focused ultrasound could destroy breast tumors before mastectomy. The procedure was to be done under local anesthesia and sedation. However, the trial was withdrawn before enrolling any participants, so no results are available.

This study was designed to observe changes in certain immune system proteins (chemokines) in the blood and urine of men with prostate cancer over time. Researchers planned to collect samples from patients starting new treatments, but the study was withdrawn before any participant…

This study aimed to understand why some women develop chronic pain after breast cancer surgery. Researchers planned to track psychological and social factors in women undergoing mastectomy or lumpectomy. However, the study was withdrawn before it started, so no results are availa…