Glycyx Therapeutics

This pilot study tested a drug called TD-1211 in 95 people who had constipation from taking opioid pain medications. The main goal was to see if the drug was safe and tolerable. Researchers also looked at whether it increased the number of complete and spontaneous bowel movements…

This study tested a drug called TD-1211 in healthy volunteers and people with constipation caused by opioid painkillers. The goal was to see if it is safe and helps with bowel movements. Participants took different doses of TD-1211 or a placebo, and researchers monitored their sa…

This study tested a drug called TD-1211 in 217 adults who have constipation because of opioid painkillers. The goal was to see if it safely increases the number of complete spontaneous bowel movements each week. Participants took either the study drug or a placebo for several wee…

This study tested a new drug called TD-1211 in 69 adults who had constipation because of opioid painkillers. The goal was to see if the drug is safe and helps people have more bowel movements. Participants stopped using other laxatives during the study to see how well TD-1211 wor…

This early-stage study looked at how a single dose of TD-1211 is processed in the body when taken with itraconazole, a drug that blocks certain liver enzymes. Twenty healthy adults aged 18 to 50 participated. The goal was to measure drug levels in the blood and check for side eff…

This study looked at how the body processes TD-1211, a drug for opioid-induced constipation. Ten healthy men received a single dose of the drug with a radioactive tracer to track its absorption, distribution, and elimination. The goal was to understand the drug's behavior, not to…

This early-stage study tested a single dose of TD-1211, an experimental drug for constipation, in 47 healthy adults split into younger (18-45) and older (65-85) groups. Researchers measured how the body absorbs and eliminates the drug and checked for side effects. The goal was to…