Fractyl Health Inc.

This study tests a procedure called Revita DMR, which uses a thin tube to treat the lining of the upper gut, to help people with obesity keep weight off after they stop taking the weight-loss drug tirzepatide. About 315 participants who lost at least 15% of their body weight on t…

This study tests a procedure called duodenal mucosal resurfacing (DMR) using the Revita system in people with type 2 diabetes whose blood sugar is not well controlled with medication. About 320 adults will be randomly assigned to receive either the real procedure or a sham (fake)…