Eye & Ent Hospital Of Fudan University

This study tests whether combining two drugs (becotatug vedotin and epirubicin) can shrink a rare type of sinus cancer that has come back and cannot be removed with surgery. About 40 adults with EGFR-positive tumors will receive the treatment to see if it makes the cancer small e…

This study follows 300 deaf patients of all ages who are getting a cochlear implant. Researchers will test hearing, speech, and quality of life before and after the implant to see how well it works for different age groups. The goal is to create better, personalized rehabilitatio…

This study tests whether vision therapy (eye exercises) or wearing prism glasses works better for people with a small-angle eye turn (esotropia) that started recently. Researchers will measure changes in eye alignment and 3D vision. The trial involves 100 participants aged 10 to …

This study tests a new approach for a rare sinus cancer that often spreads along nerves. About 100 adults with advanced tumors will receive three sessions of targeted chemotherapy directly into the tumor's blood supply. If the tumor disappears on scans, patients may avoid surgery…

This study looks at the best way to manage cancer that has spread to neck lymph nodes in people with hypopharyngeal cancer. About 111 adults aged 18 to 75 with good overall health will be enrolled. The goal is to see which treatment approach helps patients live longer without the…

This study tests a new retinal implant (AuTNA I) in 7 adults with retinitis pigmentosa, a genetic eye disease that causes vision loss. The implant is placed under the retina and aims to safely improve light sensitivity and vision. Researchers will check safety and measure any vis…

This study tests whether adding the drug finotonlimab to chemotherapy before surgery can help people with advanced hypopharyngeal cancer live longer without the cancer coming back. About 116 adults who have not had treatment before will take part. The goal is to see if this combi…

This study is testing a combination of chemotherapy and an immunotherapy drug (tislelizumab) given before surgery for people with advanced squamous cell carcinoma of the ear canal. The goal is to shrink the tumor enough to allow surgeons to remove it while preserving important ne…

This study looks at whether adding acupuncture to standard steroid treatment helps people recover hearing after sudden hearing loss. About 256 adults will receive either real or fake acupuncture along with oral steroids for 4 weeks. The main goal is to see if hearing tests improv…

This study tests a new eye drop called JN002 for people with dry eye disease. The goal is to see if it is safe and can improve eye comfort and tear production. About 30 adults will use either the eye drop or a placebo three times a day for 28 days. Researchers will check eye heal…

This study looks at how well people with severe hearing loss can understand speech after receiving either a cochlear implant or gene therapy. Researchers will compare the two groups to see which approach leads to better hearing and speech skills. The goal is to learn more about h…

This study looks at 90 cataract patients who also have an epiretinal membrane (a thin scar on the retina). Researchers want to see if a special "functional" lens implant helps vision more than a standard lens. Participants will have their vision tested before and after surgery to…

This study looks at 1,000 people with throat cancer (laryngeal or hypopharyngeal) to compare different treatments like surgery, radiation, and chemotherapy. The goal is to see which treatments lead to the best survival rates and help preserve the voice. Results will help doctors …