Engrail Therapeutics Inc

This early study tested an experimental drug called ENX-104 in 48 adults with major depressive disorder who also experience anhedonia (loss of interest or pleasure). The main goal was to check the drug's safety and how the body processes it. Researchers measured side effects and …

This study tested a new drug called ENX-102 in 38 adults with generalized anxiety disorder (GAD). The goal was to see if the drug is safe and helps reduce anxiety symptoms. Participants received either ENX-102 or a placebo, and researchers monitored side effects and anxiety level…

This study tested an experimental drug called ENX-102 in 252 adults with generalized anxiety disorder (GAD). Participants received either the drug or a placebo for several weeks. The main goal was to see if ENX-102 reduces anxiety symptoms better than placebo, using a standard an…

This study tested an experimental drug called ENX-102 in 47 adults with social anxiety disorder. Participants received either the drug or a placebo to see if it safely reduces fear and avoidance in social situations. The main goal was to measure changes in anxiety symptoms using …

This study looked at how a new drug called ENX-104 is processed by the body in 12 healthy volunteers. Researchers compared taking the drug as a liquid versus a tablet, and whether a high-fat meal changes absorption. The goal was to gather safety and dosing information, not to tre…

This early-stage study tested a single dose of ENX-104 in 10 healthy volunteers to see how safe it is, how much of the drug reaches the brain, and how long it stays in the body. Researchers used PET scans to measure the drug's effect on brain receptors. The study is complete and …