Debiopharm International Sa

This study tests a new drug (Debio 0123) combined with standard chemotherapy (temozolomide) and radiation in adults with glioblastoma, an aggressive brain cancer. The first phase finds the safest dose; the second phase checks if the combination helps people live longer. About 116…

This study tests a new drug called Debio 1562M for people with acute myeloid leukemia (AML) that has come back or not responded to standard treatments. The trial has two phases: first, to find a safe dose, and second, to see if the drug can shrink or control the cancer. About 134…

This early-phase study tests an experimental drug called lunresertib, given alone or with other drugs, in people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to check safety, find the best dose, and see if the drug can shrink …

This study tests a new long-acting drug called Debio 4126 for people with acromegaly, a condition where the body makes too much growth hormone. The drug is given as an injection every 12 weeks and aims to keep hormone levels normal. About 119 adults who are already on similar med…

This early-stage study is testing an experimental drug called Debio 1453P in 88 healthy adults aged 18 to 55. The goal is to check if the drug is safe and how the body handles it at different doses. Participants will receive either the drug or a placebo. This study does not aim t…