New hope for advanced cancer: experimental drug combo enters human testing

NCT ID NCT04855656

First seen Jan 23, 2026 · Last updated May 05, 2026 · Updated 8 times

Summary

This early-phase study tests an experimental drug called lunresertib, given alone or with other drugs, in people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to check safety, find the best dose, and see if the drug can shrink tumors or slow their growth. About 464 adults and children aged 12 and older will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • # 1019, UCLA, Westwood Cancer Center

    COMPLETED

    Los Angeles, California, 90095, United States

  • #1001, The University of Texas M.D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • #1002, Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • #1004, Memorial Sloan Kettering Cancer Institute

    RECRUITING

    New York, New York, 10065, United States

  • #1007, Rhode Island Hospital

    RECRUITING

    Providence, Rhode Island, 02903, United States

  • #1008, Columbia University

    COMPLETED

    New York, New York, 10032, United States

  • #1010, University of Pennsylvania

    COMPLETED

    Philadelphia, Pennsylvania, 19104, United States

  • #1011, Washington University

    RECRUITING

    St Louis, Missouri, 63130, United States

  • #1012, Yale

    RECRUITING

    New Haven, Connecticut, 06520, United States

  • #1013, The University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • #1016, Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55902, United States

  • #1017, Mayo Clinic

    RECRUITING

    Jacksonville, Florida, 32224, United States

  • #1023, START Midwest

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • #1025, University of California San Francisco

    RECRUITING

    San Francisco, California, 94158, United States

  • #1027, University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22903, United States

  • #1030, Women & Infants Hospital of Rhode Island

    RECRUITING

    Providence, Rhode Island, 02903, United States

  • #1032, Northwell Health Cancer Institute

    RECRUITING

    New Hyde Park, New York, 11042, United States

  • #2001, Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 2C1, Canada

  • #2002, The Hospital for Sick Children

    COMPLETED

    Toronto, Ontario, M5G 1X8, Canada

  • #2003, The Research Institute of the McGill University Health Centre

    COMPLETED

    Montreal, Quebec, H4A 3J1, Canada

  • #3003, Sarah Cannon Research Institute

    RECRUITING

    London, W1G 6AD, United Kingdom

  • #4001, Rigshospitalet - Blegdamsvej

    RECRUITING

    Copenhagen, Denmark

Conditions

Explore the condition pages connected to this study.