Dana-farber Cancer Institute

This study is testing the safety and effectiveness of an already FDA-approved skin cancer drug called cosibelimab in two special groups of patients with advanced skin cancer. The first group includes people who have had a kidney transplant, and the second includes people who also…

This study is testing a combination of chemotherapy and an immunotherapy drug (blinatumomab) to treat a type of blood cancer called acute lymphoblastic leukemia (ALL) in adolescents and young adults. The goal is to see if this specific treatment plan is safe and effective for thi…

This study is testing a drug called elacestrant for people with advanced uterine sarcoma that is fueled by estrogen. The goal is to see if the drug can shrink or control the cancer by blocking estrogen's effects. About 30 participants with specific types of advanced uterine sarco…

This study is testing whether two experimental drugs, given alone or together before surgery, can safely shrink kidney tumors. The goal is to see if this pre-surgical treatment helps control the cancer. About 32 adults with a specific type of kidney cancer that can be surgically …

This study aims to find out if exercise can help improve heart health in young adults who survived childhood cancer. It will compare two types of exercise training—high-intensity intervals versus moderate continuous workouts—to see which is more effective. About 20 participants w…

This study is testing whether the drug pemigatinib can help control advanced gastrointestinal stromal tumors (GIST) that have a specific genetic deficiency called SDH. About 24 adults with this rare tumor type who have already tried other treatments will take the drug daily in 21…

This study is testing a blood test called Galleri that looks for signs of many different cancers. It will enroll about 100 adults who have symptoms that could be cancer. The main goal is to see how well this test works compared to standard diagnostic methods for finding cancer in…

This study is testing whether a personalized exercise program is practical and acceptable for people with stage II-III lung cancer. It will involve about 20 participants who will follow the exercise plan before, during, and after their cancer treatment. The main goal is to see if…

This study is developing an online program called On-Trac to help adult cancer survivors learn skills to manage anxiety. The program uses techniques from established talk therapies and is delivered through group video sessions and individual coaching. Researchers will test if the…

This study is testing a new smartphone app called I-STAMP, designed to help people with advanced cancer manage their pain and track their medications. Researchers want to see if the app is easy to use and helpful for patients. The study will involve about 73 participants who have…

This study is testing a new AI tool designed to help match cancer patients with clinical trials they might be eligible for. The tool scans electronic health records to identify patients whose cancer is progressing and suggests relevant trials to their doctors. The goal is to see …

This study aims to create a digital nutrition program to help cancer patients improve their diet and quality of life during and after treatment. Researchers will work with about 130 people, including patients, dietitians, and family advisors, to design and test the tool. The goal…