Clexio Biosciences Ltd.

This study tested a new drug called CLE-100 in 146 adults with major depressive disorder who were already taking standard antidepressants. The goal was to see if adding CLE-100 could further reduce depression symptoms. Participants were randomly assigned to receive either CLE-100…

This study tested an experimental drug called CLE-100 (oral esketamine) in 99 adults with major depression who did not get enough relief from at least two standard antidepressants. Participants took CLE-100 or a placebo alongside their current antidepressant for several weeks. Th…

This study tested a gel called CLE-400 on 59 adults with Notalgia Paresthetica, a condition that causes long-term itching on the back. The goal was to see if the gel reduces itch intensity better than a placebo gel. Participants applied the gel daily and reported their worst itch…