Chu De Reims
Clinical trials sponsored by Chu De Reims, explained in plain language.
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Botox doses compared for Kids' bladder control
Disease control CompletedThis study looked at children aged 3 to 15 with overactive bladder caused by nerve problems. It compared two different doses of Botox injections into the bladder muscle to see if a lower dose works just as well as a higher dose. The goal was to improve bladder capacity and reduce…
Phase: PHASE3 • Sponsor: CHU de Reims • Aim: Disease control
Last updated Jun 18, 2026 11:48 UTC
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Blood test may replace painful biopsies for melanoma patients
Diagnosis CompletedThis study looked at whether a blood test can find genetic changes in people with advanced melanoma. Normally, doctors need to take a piece of the tumor (biopsy) to check for these changes. The goal was to see if a blood sample could work just as well, making testing easier and l…
Phase: NA • Sponsor: CHU de Reims • Aim: Diagnosis
Last updated Jun 22, 2026 12:07 UTC
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New urine test could spot bladder cancer without a scope
Diagnosis CompletedThis study tested whether analyzing urine with a special light technique (spectroscopy) can accurately detect bladder cancer. Researchers collected urine samples from 899 people undergoing cystoscopy. The goal was to see if the light patterns could tell apart those with cancer fr…
Sponsor: CHU de Reims • Aim: Diagnosis
Last updated Jun 22, 2026 11:57 UTC
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New hip pain block may cut morphine use in elderly
Symptom relief CompletedThis study compared two ways to manage pain after total hip replacement: a newer ultrasound-guided nerve block (PENG block) versus standard surgical infiltration. The goal was to see which method reduces the need for strong painkillers like morphine, especially in older patients …
Phase: NA • Sponsor: CHU de Reims • Aim: Symptom relief
Last updated Jun 22, 2026 12:06 UTC
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Virtual reality goggles ease pain of back injections, study finds
Symptom relief CompletedThis study tested whether wearing a virtual reality headset during an epidural injection for lower back and leg pain can lower pain and anxiety. 116 adults received the injection either with or without the headset. The goal was to see if the immersive experience makes the procedu…
Phase: NA • Sponsor: CHU de Reims • Aim: Symptom relief
Last updated Jun 22, 2026 12:04 UTC
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Eye check showdown: human vs machine in the ICU
Knowledge-focused CompletedThis study looked at how well doctors, residents, and nurses can check a patient's pupils compared to a special device called a pupillometer. Pupil checks are important in the ICU to see how the brain is doing. The study included 30 ICU patients and compared the human assessments…
Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 23, 2026 22:04 UTC
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Blood test could reveal hidden frailty in elderly cancer patients
Knowledge-focused CompletedThis study looked at whether measuring elastin fragments in blood or urine can help assess frailty in people aged 65 and older with cancer. Frailty is hard to measure with current methods, which are often subjective and slow. The goal is to find a more objective biological marker…
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 23, 2026 22:02 UTC
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Routine CT scan after pancreatic surgery may catch silent complications
Knowledge-focused CompletedThis study looked at whether a CT scan done 7 days after pancreatic surgery could find complications that doctors hadn't noticed yet. Researchers followed 80 patients who had planned pancreatic surgery. The goal was to see if the scan could detect issues like leaks or infections …
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 23, 2026 12:00 UTC
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Hidden lung damage common in immune deficiency patients
Knowledge-focused CompletedThis completed study in France looked at how common bronchiectasis (permanent lung damage) is in 46 adults with primary humoral immunodeficiency, a condition that weakens the immune system. Participants had a chest CT scan and lung function tests to check for bronchiectasis. The …
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:59 UTC
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Could your genes predict blindness from diabetes?
Knowledge-focused CompletedThis study examined whether certain genes are linked to a severe form of diabetic eye disease called proliferative diabetic retinopathy (PDR). Researchers analyzed DNA from 302 people with type 2 diabetes, some with PDR and some without. The goal was to find genetic markers that …
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:58 UTC
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Laser light may reveal hidden clues in rare skin disease
Knowledge-focused CompletedThis study tested whether a special laser technique called Raman spectroscopy can measure skin fibrosis (hardening) in people with systemic sclerosis, a rare autoimmune disease. Twenty-six adults with the condition had their skin scanned with the laser. The goal was to see if thi…
Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:09 UTC
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Blood protein gene may influence Alzheimer's risk
Knowledge-focused CompletedThis study looked at whether a specific genetic variation in a blood protein called CR1 makes people more likely to develop Alzheimer's disease. Researchers compared 200 Caucasian adults—some with Alzheimer's and some without—to see if the CR1 gene's structure or activity differe…
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:08 UTC
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Lab study digs into skin inflammation to uncover HS secrets
Knowledge-focused CompletedThis study looked at skin samples from 20 people with hidradenitis suppurativa (HS) who had surgery. Researchers measured different inflammatory proteins in the lab to understand what drives the disease. The goal was to learn more about how inflammation works in HS, not to test a…
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:07 UTC
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Could pesticides in your body raise pancreatic cancer risk?
Knowledge-focused CompletedThis study looked at whether certain chemicals called organochlorines, which are stored in body fat, are linked to pancreatic cancer. Researchers compared levels of these chemicals in fat and urine samples from 56 people with and without pancreatic cancer. The goal was to better …
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:06 UTC
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Scientists investigate protein that may predict corneal graft failure
Knowledge-focused CompletedThis study looked at 43 adults who had corneal transplant surgery. Researchers checked the new blood and lymph vessels that grow in the cornea after transplant to see if a protein called CD160 is present. The goal was to learn whether CD160 might be linked to graft rejection, whi…
Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:04 UTC
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Scientists use brain scans to unravel bipolar thought problems
Knowledge-focused CompletedThis study used functional MRI to look at brain activity in people with bipolar disorder who experience thought disorders, like racing ideas or trouble staying on topic. Researchers compared 79 participants (patients and healthy controls) while they performed language tasks. The …
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:59 UTC
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Study reveals driving risks in early Alzheimer's – and how to stay safe
Knowledge-focused CompletedThis study looked at driving skills in 60 people over age 70 with early-stage Alzheimer's disease (MMSE score 24 or higher) and compared them to healthy older drivers. The goal was to identify common driving mistakes and suggest adaptive measures or technology to help them drive …
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:55 UTC
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New test could reveal if arthritis patients are taking their meds
Knowledge-focused CompletedThis study looked at how the drug methotrexate and its main byproduct leave the body in people with rheumatoid arthritis. Researchers measured levels in urine to create a reference range. This could help doctors identify patients who are not taking their medication as prescribed.
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:51 UTC
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Dialysis danger: scientists probe hidden culprits behind heart risks
Knowledge-focused CompletedThis study looked at 100 kidney dialysis patients to understand why their blood vessels get damaged, raising heart risks. Researchers measured harmful substances called AGEs in the blood and skin, and checked for genetic factors. The goal was to learn how these substances interac…
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:50 UTC