Could your genes predict blindness from diabetes?
NCT ID NCT02879422
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study examined whether certain genes are linked to a severe form of diabetic eye disease called proliferative diabetic retinopathy (PDR). Researchers analyzed DNA from 302 people with type 2 diabetes, some with PDR and some without. The goal was to find genetic markers that might help predict who is at higher risk for vision-threatening eye disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If certain genes are found to be linked to severe diabetic eye disease, this could help identify people at higher risk earlier.
- What could go wrong
- This is an observational study, not a treatment trial. It only looks for genetic links, so it cannot directly lead to a new therapy. The results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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302 people
The number who actually took part.
- Started
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Oct 2013
- Finished
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Jan 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * type 2 diabetic patients * patient with proliferative diabetic retinopathy (for arm 1) * patient with non proliferative diabetic retinopathy (for arm 2) * patient older than 18 years * patient consenting to participate to the study * patient enrolled in the national healthcare insurance program
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chu de Reims
Reims, 51092, France
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