Children's National Research Institute

This study tests whether a medicine called Amicar (EACA) can reduce blood loss in children aged 2 to 36 months who need skull reconstruction for a condition called craniosynostosis. The trial involves 22 children, half receiving Amicar and half receiving a placebo (salt water). T…

This early-stage study tests whether immune cells grown from a donor's blood can safely fight or prevent seven different viruses in people who have had a bone marrow transplant. About 32 participants will receive these cells either as a preventive measure or as a treatment for ac…

This early-phase trial tests a new type of cell therapy for children and young adults with solid tumors that have come back or not responded to standard treatments. The therapy uses a patient's own immune cells, which are trained in the lab to recognize and attack multiple cancer…

This study tests a program called FACE-Rare, designed to support family caregivers of children with rare, life-limiting diseases. The program includes three sessions to help families prepare for future medical decisions and improve their quality of life. Researchers will compare …

This study looks at whether a group therapy program called Unstuck & On Target can improve flexibility and learning in 64 teens with autism aged 14-18. Researchers will use brain scans (MRI) to see if the therapy changes how the brain processes new information. The goal is to und…

This study tests whether a new educational tool helps medical learners get more out of their pediatric palliative care rotation. About 30 adult learners will use the tool during their rotation and then answer survey questions about their experience. Researchers will compare their…