Children's National Research Institute

This early-stage trial tests a new treatment for children and young adults with high-risk solid tumors that have not responded to standard therapy. The approach uses a patient's own immune cells, trained to recognize multiple cancer targets, to attack the tumor. The main goal is …

This early-stage trial tests whether specially grown immune cells from a donor can safely prevent or treat seven common viruses in people who have received a stem cell transplant. About 32 participants will receive these cells either as a preventive measure or to fight an active …

This study tests whether Amicar (ε-aminocaproic acid) can reduce blood loss in children aged 2 to 36 months undergoing surgery for craniosynostosis, a condition where skull bones fuse too early. The goal is to see if the drug decreases the need for blood transfusions during and a…

This study looks at the unmet palliative care needs of children with rare diseases and their family caregivers. Researchers will test a program called FACE-Rare to see if it helps families prepare for medical decisions and improves quality of life. About 480 families will take pa…

This study looks at how a cognitive-behavioral program designed to improve flexibility changes learning and brain activity in teens with autism. Researchers will use brain scans and behavior tests to see if the program helps teens learn better. The study involves 64 teens aged 14…

This study looks at whether a new educational tool helps doctors and nurses in training get more out of their pediatric palliative care rotation. About 30 adult learners will use the tool and then answer survey questions about their experience. Researchers will compare their answ…