Central South University

This study tests whether a probiotic called Akkermansia muciniphila (AKK PROBIO) can help obese children and adolescents aged 7 to 18 improve their weight and metabolism. Half of the 100 participants will take the probiotic capsules, and half will take a placebo. The goal is to s…

This clinical trial is testing a non-invasive brain stimulation method called temporal interference transcranial alternating current stimulation (TI-tACS) for people with major depressive disorder or generalized anxiety disorder. The device uses two high-frequency electrical curr…

This study tests whether a gentle brain stimulation technique called tACS can make mindfulness therapy work better for people with generalized anxiety disorder. 99 adults will receive either real or fake tACS while doing mindfulness exercises. Researchers will track anxiety sympt…

This study tests a faster version of brain stimulation for generalized anxiety disorder. Instead of weeks of treatment, participants receive five sessions per day for five days. The stimulation is guided by each person's MRI scan to target a specific brain area linked to anxiety.…

This research looks at how brain networks relate to thinking and memory problems in people with schizophrenia, bipolar disorder, or major depression. The goal is to use brain imaging to better assess cognitive issues, improve diagnosis, and predict how well treatments might work.…