Biogen

This study looked at whether adding a medicine called nusinersen can help children under 3 with spinal muscular atrophy (SMA) who still have muscle problems even after receiving gene therapy. The 46 children received several doses of nusinersen over about 2 years. Researchers che…

This study tested a new drug called BIIB091, alone or combined with an existing MS drug (diroximel fumarate), in 127 people with relapsing forms of multiple sclerosis. The goal was to check safety and see if the drug reduces brain inflammation. Participants took pills twice daily…

This study tested the safety and tolerability of a drug called diroximel fumarate in 136 adults from the Asia-Pacific region with relapsing forms of multiple sclerosis (MS). Participants took the drug for up to 48 weeks, and researchers monitored side effects, lab results, and ho…

This study tested a drug called RTA 408 (omaveloxolone) in 172 people with Friedreich's ataxia, a rare nerve disease that affects movement and coordination. The main goals were to see if the drug is safe and if it can improve exercise ability and daily function. Participants took…

This study tested a drug called nusinersen in 25 infants who have the genetic markers for spinal muscular atrophy (SMA) but do not yet have symptoms. The goal was to see if giving the drug early could prevent or delay the need for breathing support or death. The drug is given via…

This study looked at how the body processes the drug omaveloxolone (SKYCLARYS®) when taken as a whole capsule versus sprinkled over low-fat yogurt. 52 healthy adults each took the drug both ways, with a 14-day break in between. The goal was to see if yogurt is a good alternative …

This study looked at how a drug being tested for Alzheimer's disease, called BIIB080, spreads through the brain and spinal cord. Five healthy adults received a tiny radioactive version of the drug along with a regular dose, then had PET scans to track it. The main goal was to mea…

This study tested three different devices (a pre-filled syringe, an autoinjector, and an on-body injector) to give the drug litifilimab under the skin. The goal was to see how the body processes the drug with each device. 404 healthy volunteers took part, and the study focused on…

This study looked at how the drug omaveloxolone (used for Friedreich's Ataxia) affects the way the body processes omeprazole, a common heartburn medication. Twenty-two healthy adults took both drugs in a specific order over 17 days. Researchers measured omeprazole levels in the b…

This study tested a new drug called BIIB800 against the approved drug Actemra in 300 healthy men. The goal was to see if the body processes both drugs similarly and to check for side effects. Participants received a single injection and were monitored over time. No treatment was …