Bicycletx Limited

This study tests an experimental drug, zelenectide pevedotin, in people with advanced non-small cell lung cancer that has a specific genetic change (NECTIN4 amplification) and has already been treated with at least one prior therapy. The goal is to see if the drug can shrink tumo…

This study tests a new drug called BT8009, alone or with another drug (pembrolizumab), in people with advanced solid tumors that have a protein called Nectin-4. The goal is to see if the drug is safe and shrinks tumors. About 329 adults with cancers like bladder, breast, lung, or…

This study tests a new drug, BT5528, given alone or with another drug (nivolumab) in people with advanced solid tumors that have high levels of a protein called EphA2. The main goals are to find safe doses and learn about side effects. The study also checks if the drug can shrink…

This study tests an experimental drug, zelenectide pevedotin, in people with advanced breast cancer that has a specific genetic change called NECTIN4 amplification. The trial includes two groups: one with hormone receptor-positive/HER2-negative cancer and another with triple-nega…

This study tests a new drug called BT8009, alone or with another drug (pembrolizumab), for people with advanced bladder cancer that has spread. The goal is to see if it helps shrink tumors or slow the disease. About 956 adults who have not had treatment or have had prior therapy …

This study tests a new drug called BT7480, alone or with another drug (nivolumab), in about 200 people with advanced solid tumors that have not responded to standard treatments. The goal is to find a safe dose and see if the drug shrinks tumors or slows cancer growth. Participant…