New drug combo shows promise for Hard-to-Treat cancers
NCT ID NCT05163041
First seen Jan 18, 2026 · Last updated May 07, 2026 · Updated 15 times
Summary
This study tests a new drug called BT7480, alone or with another drug (nivolumab), in about 200 people with advanced solid tumors that have not responded to standard treatments. The goal is to find a safe dose and see if the drug shrinks tumors or slows cancer growth. Participants must have tumors linked to a protein called Nectin-4, such as certain bladder, lung, or ovarian cancers.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Columbia University Irving Medical Center
New York, New York, 10032, United States
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Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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START Center for Cancer Care
San Antonio, Texas, 78229, United States
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State University of Iowa
Iowa City, Iowa, 52242, United States
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The Beatson West of Scotland Cancer Centre
Glasgow, G12 0YN, United Kingdom
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The Royal Marsden NHS Foundation Trust
Sutton, Surrey, SM2 5PT, United Kingdom
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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Virginia Cancer Specialists
Fairfax, Virginia, 22031, United States
Conditions
Explore the condition pages connected to this study.