Azienda Ospedaliera Specializzata In Gastroenterologia Saverio De Bellis

This study aims to find molecular clues that could predict whether certain pancreatic growths will turn into cancer. Researchers will analyze tissue from patients having pancreatic surgery, using advanced genetic and protein tests on both the original tissue and lab-grown 3D cell…

This study looks at whether a common blood test called FIB-4 can accurately predict liver fibrosis (scarring) in people with obesity. Researchers will compare FIB-4 results with liver stiffness measurements from a specialized scan (FibroScan) in 400 obese patients. If the blood t…

This study looks at whether adding Cognitive Behavioral Therapy (CBT) to standard medical care can reduce stomach symptoms in adults with functional dyspepsia, a condition causing pain or discomfort after eating. About 90 adults aged 18-65 will be randomly assigned to receive eit…

This study looks at two types of liver disease — autoimmune hepatitis and non-alcoholic fatty liver disease — to see if fats in blood cells and tiny particles called extracellular vesicles differ between them. Researchers will collect blood samples from 24 adults and analyze thes…

This study investigates why some stomach cancers do not respond to a standard chemotherapy combination (FLOT) plus the immunotherapy drug durvalumab. Researchers will analyze tumor samples and blood from 250 patients with operable stomach or gastroesophageal junction cancer. By m…

This study looks at why colorectal cancer spreads to the liver. Researchers will collect tumor samples from 156 patients during surgery to study a protein called SMYD3. They believe SMYD3 helps cancer cells survive and grow in the liver by changing how cells use energy and handle…

This observational study tracks 100 adults to see how Roux-en-Y gastric bypass surgery changes gut bacteria and related metabolic products over 12 months. Participants include people having surgery, those with obesity on diet alone, and healthy normal-weight individuals. Research…