Australian And New Zealand Intensive Care Research Centre

This study tests two approaches for treating septic shock in 1000 emergency department patients. One group gets less IV fluid and early blood-pressure-raising drugs (vasopressors), while the other gets more fluid first and vasopressors later if needed. The goal is to see which me…

This study tests whether giving sodium bicarbonate (a common acid neutralizer) to adults in the intensive care unit with metabolic acidosis and shock can reduce the risk of serious kidney problems or death within 30 days. About 500 participants receive either the bicarbonate solu…