Amsterdam Umc, Location Vumc

This study compares the standard fixed-interval dosing of ocrelizumab (every 24 weeks) with a personalized approach where infusions are given only when B cell levels rise above a certain threshold. The goal is to see if the personalized schedule is just as good at preventing rela…

This study tests whether the anti-inflammatory drug celecoxib can help people with a specific type of depression linked to inflammation, called immuno-metabolic depression (IMD). Researchers will give 140 people with IMD either celecoxib or a placebo, in addition to their usual d…

This study tests a Participatory Approach to prevent work-related mental health problems by tailoring stress-reduction programs to each organization's unique needs. Over 1,000 employees from four different Dutch companies will take part. The goal is to find common patterns that m…

This study tests whether a short, intensive course of cognitive behavioral therapy (CBT) over 2 weeks works better than the usual weekly sessions over 6 months for people with anxiety disorders. 120 adults with conditions like panic disorder, OCD, or PTSD will be randomly assigne…

This study involves 15 postmenopausal women with metastatic ER+ breast cancer. Researchers are testing a special PET scan that uses a radioactive tracer to see estrogen receptors on tumors. The goal is to find the best way to measure these receptors, which could help doctors know…