Ahs Cancer Control Alberta

This study compares two ways of using thyroid hormone (levothyroxine) to suppress TSH in people with advanced thyroid cancer that has spread or returned. The current standard keeps TSH very low (below 0.1), but this can cause side effects. The study will test if a slightly higher…

This study is for men with high-risk prostate cancer that hasn't spread to lymph nodes. It uses PSMA-PET scans to precisely target radiation to the prostate and nearby tissues, with or without whole pelvis radiation. The goal is to improve cancer control and reduce side effects. …

This study tests a new way to give radiation for prostate cancer using only two treatments instead of the usual five or more. Doctors will use MRI scans to see how the tumor responds after the first dose, then adjust the second dose to target it more precisely. The goal is to saf…

This study tests whether giving immunotherapy (pembrolizumab) in the morning works better than giving it at any random time for people with advanced non-small cell lung cancer. About 58 participants will be split into two groups: one gets infusions only between 8-10 AM, the other…

This study tests whether adding the targeted drug olaparib to the chemotherapy temozolomide helps control a specific type of triple-negative breast cancer that has spread or cannot be removed by surgery. About 40 adults with a genetic marker called MGMT methylation will be random…

This study looks at adding a precise, high-dose radiation treatment called SBRT to standard chemotherapy and immunotherapy for people with esophageal cancer that has spread to a few other spots in the body. The goal is to see if this combination can help control the disease longe…