Ahs Cancer Control Alberta

This study tests a new way to give radiation for prostate cancer using only 2 treatments instead of the usual 39. Doctors will use MRI scans to see how the tumor responds after the first dose, then adjust the second dose to target the cancer more precisely. The goal is to see if …

This study compares two strategies for using levothyroxine to suppress TSH in patients with advanced thyroid cancer that cannot be fully removed. The standard approach keeps TSH very low (below 0.1), but this can cause side effects. The trial will test if a slightly higher TSH ta…

This study looks at adding a precise, high-dose radiation treatment called SBRT to standard chemotherapy and immunotherapy for people with esophageal cancer that has spread to a few other spots in the body. The goal is to see if this combination can help control the cancer longer…

This study tests whether using PSMA-PET scans to guide radiation therapy can improve cancer control in men with high-risk prostate cancer that hasn't spread to lymph nodes. About 250 participants will receive radiation to the prostate and nearby tissues, with or without whole pel…

This study tests whether adding a targeted drug (olaparib) to a standard chemotherapy (temozolomide) can better control advanced triple-negative breast cancer that has a specific genetic marker (MGMT methylation). About 40 adults with this cancer type will be randomly assigned to…

This study looks at whether giving pembrolizumab infusions in the morning improves outcomes for people with metastatic non-small cell lung cancer. 58 participants will be randomly assigned to morning or standard scheduling. The goal is to see if timing affects how long the cancer…