New combo targets hard-to-treat breast cancer in early trial

NCT ID NCT05128734

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a targeted drug (olaparib) to a standard chemotherapy (temozolomide) can better control advanced triple-negative breast cancer that has a specific genetic marker (MGMT methylation). About 40 adults with this cancer type will be randomly assigned to receive either the chemotherapy alone or the combination. The main goal is to see how many patients have their tumors shrink or stop growing.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arthur J.E. Child Comprehensive Cancer Centre

    Calgary, Alberta, T2N 5G2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

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