XEROSTOMIA
Clinical trials for XEROSTOMIA explained in plain language.
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Whitening serum may freshen breath and moisturize mouth
Symptom relief OngoingThis study tested whether Crest Daily Whitening Serum can reduce dry mouth and bad breath in 27 adults who already have these issues. Participants used the product for one week and reported their symptoms. The goal was to see if a simple whitening gel could provide quick relief f…
Matched conditions: XEROSTOMIA
Phase: NA • Sponsor: Tufts University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Could arginine toothpaste be the answer to dry mouth?
Symptom relief OngoingThis study tests whether an arginine-containing toothpaste can change the acidity of saliva in people with dry mouth caused by medications. Seventy adults will use either the arginine toothpaste or a regular fluoride toothpaste for 12 weeks. Researchers will measure saliva pH and…
Matched conditions: XEROSTOMIA
Phase: PHASE3 • Sponsor: Tufts University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Stem cells aim to quench Radiation-Induced dry mouth in cancer survivors
Symptom relief OngoingThis early-phase study tests whether injecting a person's own bone marrow stem cells into their salivary glands is safe and tolerable for treating dry mouth caused by radiation therapy for head and neck cancer. About 23 participants who finished radiation at least 2 years ago wil…
Matched conditions: XEROSTOMIA
Phase: PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Throat cancer radiation trial targets saliva ducts to stop dry mouth
Symptom relief TerminatedThis study aimed to see if using MRI scans to guide radiation away from the main saliva ducts could reduce dry mouth in people with oropharynx cancer. The trial planned to compare standard radiation with a new approach that spares these ducts. However, the study was withdrawn bef…
Matched conditions: XEROSTOMIA
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 26, 2026 13:32 UTC
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Radiation's hidden toll: study tracks Long-Term dental damage in cancer patients
Knowledge-focused OngoingThis study follows 100 head and neck cancer patients receiving standard radiotherapy to see how their teeth, gums, and saliva change over time. Researchers measure gum health, tooth condition, and quality of life before and after treatment. The goal is to better understand these …
Matched conditions: XEROSTOMIA
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC