XEROSTOMIA

This early-stage study is testing whether injecting a person's own bone marrow stem cells into their salivary glands is safe and might help relieve severe, persistent dry mouth caused by radiation treatment for head and neck cancer. Up to 23 participants who are at least 2 years …

This study aimed to test whether using detailed MRI scans to guide radiation treatment could help reduce severe, long-lasting dry mouth in people receiving radiation for throat cancer. Researchers planned to compare a new approach that specifically avoids damaging key saliva duct…

This study is testing whether a Crest whitening serum gel can help reduce feelings of dry mouth and bad breath over one week of use. It involves 27 adults who have dry mouth caused by their regular medications. Researchers will measure changes by asking participants to rate their…

This study is testing whether a toothpaste containing arginine can improve the oral environment for people with dry mouth caused by medications. Seventy adults who take at least two medications known to cause dry mouth will use the toothpaste for 12 weeks. Researchers will measur…

This study aims to understand how radiation therapy for head and neck cancer affects a patient's teeth, gums, and saliva over time. Researchers will follow 100 patients from before their radiation treatment through one year after, measuring changes in gum health, tooth decay, and…