XEROSTOMIA
Clinical trials for XEROSTOMIA explained in plain language.
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Toothpaste breakthrough: arginine formula may soothe dry mouth sufferers
Symptom relief OngoingThis study tests whether an arginine-containing toothpaste can improve dry mouth (xerostomia) by changing saliva acidity and oral bacteria. About 70 adults with dry mouth from medications will use the toothpaste for 12 weeks. The goal is to see if it makes the mouth less acidic a…
Matched conditions: XEROSTOMIA
Phase: PHASE3 • Sponsor: Tufts University • Aim: Symptom relief
Last updated May 17, 2026 01:59 UTC
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Tooth whitener may also freshen breath and moisturize mouth
Symptom relief OngoingThis study tested whether a daily whitening serum (Crest Daily Whitening Serum) can reduce dry mouth and bad breath in 27 adults who already have dry mouth. Participants used the product for one week and reported their symptoms. The goal was to see if the gel improves comfort and…
Matched conditions: XEROSTOMIA
Phase: NA • Sponsor: Tufts University • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Stem cells aim to quench Radiation-Induced dry mouth
Symptom relief OngoingThis early-phase study tests whether injecting a person's own bone marrow stem cells into their salivary glands can safely reduce dry mouth caused by radiation therapy for head and neck cancer. About 23 adults who finished radiation at least 2 years ago and have no active cancer …
Matched conditions: XEROSTOMIA
Phase: PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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New MRI technique aims to spare throat cancer patients from lifelong dry mouth
Symptom relief TerminatedThis study was designed to see if using MRI scans to guide radiation therapy can better protect the salivary ducts and reduce dry mouth in people with oropharynx cancer. Dry mouth is a common and lasting side effect of radiation. The plan was to compare patient-reported dry mouth…
Matched conditions: XEROSTOMIA
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 13, 2026 15:59 UTC
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Radiation's hidden toll on smiles: new study tracks oral damage in cancer patients
Knowledge-focused OngoingThis study follows 100 head and neck cancer patients receiving radiotherapy to see how it affects their teeth, gums, and saliva over time. Researchers measure gum health and dental changes before and after treatment. The goal is to better understand long-term oral side effects an…
Matched conditions: XEROSTOMIA
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC