UVEITIS

This study tested three biologic drugs (adalimumab, anakinra, and tocilizumab) in 112 people with severe, non-infectious uveitis that did not improve with standard treatments. The goal was to see which drug best reduces eye inflammation and allows patients to lower their steroid …

This study checked whether patients with rheumatoid arthritis, spondyloarthritis, Crohn's disease, or uveitis could safely switch from the original drug Remicade to its lower-cost biosimilar Inflectra. Researchers followed 262 adults at one hospital who had already received at le…

This study followed 30 people with uveitis (eye inflammation) who received a fluocinolone acetonide implant. Researchers used special eye scans to measure inflammation changes over 12 months. The goal was to see how the implant affects inflammation and vision, not to test a new t…

This study tested a gel form of ACTH, a natural hormone, to treat non-infectious uveitis (eye inflammation). 28 adults with active inflammation received one of two doses of the gel as a shot under the skin. The goal was to see if it is safe and can reduce eye inflammation. The st…

This study tested whether the drug adalimumab could reduce eye inflammation in children with juvenile arthritis whose eye problems weren't helped by standard steroid drops and methotrexate. For the first two months, some children received adalimumab while others received a placeb…

This study tested whether a step-by-step diagnostic plan for uveitis (eye inflammation) works as well as letting doctors choose tests freely, while costing less. Over 900 adults with uveitis took part. The goal was to see if the standardized approach could find the cause of uveit…

This study looked at the natural bacteria in the gut of 131 adults—some with uveitis (an inflammatory eye disease) and some healthy—to see if differences in gut microbes are linked to eye inflammation. Participants provided stool and blood samples and had eye exams, but no treatm…

This study collected blood, tissue, and other samples from 343 people with uveitis (a serious eye disease) to learn why some people get it and how they respond to treatment. Participants were followed for up to 10 years with eye exams and tests. The goal was to gather information…