UROTHELIAL CARCINOMA (UC)
Clinical trials for UROTHELIAL CARCINOMA (UC) explained in plain language.
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Could a drug combo spare bladder cancer patients from surgery?
Disease control Not yet recruitingThis phase 2 trial tests a combination of two drugs, enfortumab vedotin and pembrolizumab, given before surgery to people with muscle-invasive bladder cancer or upper tract urothelial carcinoma. The goal is to see if the drugs can shrink or eliminate the cancer enough that some b…
Matched conditions: UROTHELIAL CARCINOMA (UC)
Phase: PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New drug duo takes on advanced bladder cancer in early trial
Disease control Not yet recruitingThis study tests a new drug called AK146D1, given alone or with another drug (AK112), in people with advanced urothelial carcinoma (a type of bladder cancer). The goal is to see if the treatment is safe and can shrink tumors. About 132 adults aged 18-75 with measurable tumors and…
Matched conditions: UROTHELIAL CARCINOMA (UC)
Phase: PHASE2 • Sponsor: Akeso • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New hope for advanced HER2 cancers? drug trial launches
Disease control Not yet recruitingThis early-phase study tests a drug called zanidatamab in 10 adults with advanced HER2-positive solid tumors (like endometrial, bladder, or pancreatic cancer) that have worsened after at least one prior treatment. Participants receive the drug by IV every two weeks. The main goal…
Matched conditions: UROTHELIAL CARCINOMA (UC)
Phase: PHASE2 • Sponsor: Haihua Yuan • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New drug targets hard-to-treat cancers in early trial
Disease control Not yet recruitingThis study tests a drug called Trastuzumab Rezetecan in 15 adults with advanced solid tumors that have the HER2 protein. The goal is to see if the drug can shrink tumors. Participants get the drug by IV every 3 weeks. This is for people whose cancer has worsened after other treat…
Matched conditions: UROTHELIAL CARCINOMA (UC)
Phase: PHASE2 • Sponsor: Haihua Yuan • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Electric shocks and calcium: a new hope for bladder cancer?
Disease control Not yet recruitingThis early-stage trial tests a procedure called calcium electroporation for bladder tumors. Doctors inject calcium into the tumor and then apply short electric pulses to destroy cancer cells. The study will include 20 patients who cannot have standard surgery or other treatments.…
Matched conditions: UROTHELIAL CARCINOMA (UC)
Phase: PHASE1 • Sponsor: Juan Luis Vásquez • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New biosimilar aims to match cancer drug OPDIVO at lower cost
Disease control Not yet recruitingThis Phase 1 trial tests whether HLX18, a biosimilar of the cancer drug OPDIVO, works similarly in people with esophageal, melanoma, or bladder cancer after their tumors have been surgically removed. About 174 participants will receive either HLX18 or OPDIVO to compare how the dr…
Matched conditions: UROTHELIAL CARCINOMA (UC)
Phase: PHASE1 • Sponsor: Shanghai Henlius Biotech • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New study tests Nerve-Saving support for bladder cancer patients
Symptom relief Not yet recruitingThis study looks at whether a supportive product called Neuridase can help reduce nerve damage (peripheral neuropathy) caused by a combination of two cancer drugs (enfortumab vedotin and pembrolizumab) in people with advanced bladder cancer. About 40 participants will receive sta…
Matched conditions: UROTHELIAL CARCINOMA (UC)
Phase: NA • Sponsor: University of Florence • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Scientists hunt for clues in bladder Cancer's surrounding tissue
Knowledge-focused Not yet recruitingThis study examines stored tumor samples from 100 bladder cancer patients who had their bladder removed. Researchers will measure the amount of supportive tissue, immune cells, and immune clusters near the tumor. The goal is to see if these features are linked to how long patient…
Matched conditions: UROTHELIAL CARCINOMA (UC)
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC