UROTHELIAL CANCER
Clinical trials for UROTHELIAL CANCER explained in plain language.
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Nanoparticle chemo and DNA-Repair blocker join forces against tough cancers
Disease control CompletedThis trial investigates a combination of two drugs: EP0057, a chemotherapy drug wrapped in a nanoparticle to help it reach cancer cells, and olaparib, which stops cancer cells from fixing DNA damage. The study includes adults with small cell lung cancer, bladder cancer, or prosta…
Matched conditions: UROTHELIAL CANCER
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Immunotherapy combo may delay progression in advanced bladder cancer
Disease control CompletedThis study tested whether a combination of two immunotherapy drugs (nivolumab and ipilimumab) could help keep advanced bladder cancer from growing after initial chemotherapy. It involved 25 adults whose cancer had not worsened after first-line chemo. The goal was to see if this m…
Matched conditions: UROTHELIAL CANCER
Phase: PHASE2 • Sponsor: Spanish Oncology Genito-Urinary Group • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New clip could make robotic cancer surgery safer
Disease control CompletedThis study tested a new surgical clip called VasoClip, designed to hold blood vessels closed more securely during robotic surgery for prostate, kidney, or bladder cancer. Forty patients were randomly assigned to receive either the new clip or a standard clip. The goal was to see …
Matched conditions: UROTHELIAL CANCER
Phase: PHASE3 • Sponsor: Incheon St.Mary's Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Drug combo shows promise for tough cancers
Disease control CompletedThis early-phase trial tested a combination of two drugs—pembrolizumab (an immunotherapy) and nintedanib (a drug that blocks blood vessel growth)—in 196 adults with advanced solid tumors that had worsened after standard treatment. The main goal was to find the safest dose of nint…
Matched conditions: UROTHELIAL CANCER
Phase: PHASE1 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New drug outshines chemo in advanced bladder cancer trial
Disease control CompletedThis study tested a new drug called enfortumab vedotin against standard chemotherapy in 608 adults with advanced bladder or urinary tract cancer that had spread or come back after prior treatment. The goal was to see if the new drug helped people live longer and slowed cancer gro…
Matched conditions: UROTHELIAL CANCER
Phase: PHASE3 • Sponsor: Astellas Pharma Global Development, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Real-World data shows avelumab helps control advanced bladder cancer after chemo
Disease control CompletedThis study looked at 106 adults with advanced bladder cancer that hadn't gotten worse after initial chemotherapy. They received avelumab as a maintenance treatment to help keep the cancer under control. Researchers tracked how long patients lived and any side effects in real-worl…
Matched conditions: UROTHELIAL CANCER
Sponsor: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Bladder cancer treatment patterns under the microscope
Knowledge-focused CompletedThis study looks at how adults with advanced bladder cancer are treated in everyday medical practice, not in a controlled trial. Researchers will analyze data from cancer clinics to see how long patients go without their disease worsening after starting their first treatment. The…
Matched conditions: UROTHELIAL CANCER
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Bladder cancer drugs under the microscope: do they work in everyday practice?
Knowledge-focused CompletedThis observational study followed 35 adults with advanced urothelial (bladder) cancer who had stable disease after initial chemotherapy. They received either Avelumab as first-line maintenance therapy or Pembrolizumab as second-line therapy. Researchers tracked how long the cance…
Matched conditions: UROTHELIAL CANCER
Sponsor: Azienda Ospedaliera Universitaria Integrata Verona • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC