UNDIFFERENTIATED PLEOMORPHIC SARCOMA
Clinical trials for UNDIFFERENTIATED PLEOMORPHIC SARCOMA explained in plain language.
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New cocktail aims to shrink sarcomas: bevacizumab joins chemo in phase 2 trial
Disease control Not yet recruitingThis phase 2 trial tests whether adding the drug bevacizumab (Onbevzi) to standard chemotherapy (gemcitabine and docetaxel) can shrink tumors better than chemo alone in people with advanced soft tissue sarcoma. About 92 adults who have already had 1-2 prior chemotherapies will be…
Matched conditions: UNDIFFERENTIATED PLEOMORPHIC SARCOMA
Phase: PHASE2 • Sponsor: Yonsei University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New drug cocktail takes on rare nerve tumors
Disease control Not yet recruitingThis early-phase trial tests a combination of three drugs—selumetinib, ZEN-3694, and durvalumab—in people with advanced sarcomas, including malignant peripheral nerve sheath tumors (MPNST) linked to NF1. The study first checks safety and dosing, then looks at whether the treatmen…
Matched conditions: UNDIFFERENTIATED PLEOMORPHIC SARCOMA
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Experimental drug combo takes on rare sarcomas
Disease control Not yet recruitingThis early-phase trial tests a new drug called BOLD-100 combined with standard chemotherapy (doxorubicin) in 32 people with advanced soft tissue sarcomas that cannot be removed by surgery or have spread. The goal is to find the safest dose and see if the combination can shrink tu…
Matched conditions: UNDIFFERENTIATED PLEOMORPHIC SARCOMA
Phase: PHASE1 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC