New cocktail aims to shrink sarcomas: bevacizumab joins chemo in phase 2 trial

NCT ID NCT07547592

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether adding the drug bevacizumab (Onbevzi) to standard chemotherapy (gemcitabine and docetaxel) can shrink tumors better than chemo alone in people with advanced soft tissue sarcoma. About 92 adults who have already had 1-2 prior chemotherapies will be randomly assigned to one of two groups. The main goal is to see how many patients' tumors shrink significantly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bevacizumab (Onbevzi), gemcitabine, docetaxel

What this could lead to

If adding bevacizumab works, this could give doctors a new, more effective drug combination for treating advanced soft tissue sarcoma.

What could go wrong

This is a mid-stage trial with only 92 people, so results may not apply to everyone. Adding bevacizumab also raises risks like bleeding and high blood pressure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

angiosarcoma connective and soft tissue neoplasm leiomyosarcoma liposarcoma undifferentiated pleomorphic sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••