TOBACCO DEPENDENCE
Clinical trials for TOBACCO DEPENDENCE explained in plain language.
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Texts boost quitting: new study tests simple approach
Disease control CompletedThis study tested whether text message reminders and rewards could help people who smoke to stick with their quitline counseling and take their medication. Twenty adults who smoked daily took part. They received a prescription for a stop-smoking drug and were referred to a quitli…
Matched conditions: TOBACCO DEPENDENCE
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Kids' blood tests could help parents kick the habit
Disease control CompletedThis study tests whether measuring tobacco smoke exposure in children, using a simple blood test, can help parents quit smoking. About 865 parents of young children (12 or younger) who smoke will be enrolled. The goal is to see if this approach, combined with support, leads to mo…
Matched conditions: TOBACCO DEPENDENCE
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Automated calls help cancer patients kick the habit
Disease control CompletedThis study tested a program called CareConnect that uses automated phone calls to help cancer patients stop smoking. About 400 cancer patients who smoked took part. The program gave them educational messages and connected them to resources like quitlines or websites. The goal was…
Matched conditions: TOBACCO DEPENDENCE
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Virtual coach aims to help public housing residents quit smoking
Disease control CompletedThis pilot study tested whether a virtual counselor program, combined with support from a community health worker, could help people in public housing quit smoking and get screened for lung cancer. Five participants were offered nicotine replacement therapy and two counseling ses…
Matched conditions: TOBACCO DEPENDENCE
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 26, 2026 15:45 UTC
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Can DBT help High-Risk veterans quit smoking?
Symptom relief CompletedThis study tested a new smoking cessation program for veterans who are at high risk for suicide. The program combines standard tobacco treatment with Dialectical Behavior Therapy (DBT), a therapy proven to reduce suicide risk. 67 veterans participated, and researchers measured ho…
Matched conditions: TOBACCO DEPENDENCE
Phase: NA • Sponsor: Veterans Medical Research Foundation • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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New therapy helps smokers with mental illness kick the habit
Symptom relief CompletedThis study tested a type of talk therapy called Positive Psychotherapy (PPT) to help people with serious mental illness quit smoking. Sixteen adults who smoked at least 10 cigarettes a day and wanted to quit took part. The goal was to see if at least 20% could stop smoking comple…
Matched conditions: TOBACCO DEPENDENCE
Phase: NA • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Flavored cigars may hook young smokers even more
Knowledge-focused CompletedThis study looked at whether little cigars and cigarillos (LCCs) are addictive, especially when flavored like fruit, and if addiction differs between men and women. Researchers studied 65 young adults aged 18-34 who smoke both LCCs and cigarettes. They measured how much people wo…
Matched conditions: TOBACCO DEPENDENCE
Phase: NA • Sponsor: UConn Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Baltimore pilot uses digital avatar to help smokers quit and screen for lung cancer
Knowledge-focused CompletedThis pilot study tested whether a computer avatar that delivers a smoking cessation program, combined with help from a community health worker, could help people in Baltimore public housing quit smoking and get screened for lung cancer. Ten adults aged 50 or older who smoked took…
Matched conditions: TOBACCO DEPENDENCE
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Veterans who Won't quit smoking get help through friendly calls
Knowledge-focused CompletedThis study tested whether regular support calls can help veterans who are not ready to quit smoking to eventually stop. Over 500 veterans received either four calls a year (enhanced care) or one call a year (standard care). The goal was to see if more calls led to more quit attem…
Matched conditions: TOBACCO DEPENDENCE
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Flavored vapes may rewire Brain's reward system
Knowledge-focused CompletedThis study looked at whether flavor chemicals in e-cigarettes can make them more addictive by changing brain function. 36 regular tobacco users (ages 21-60) had their brain activity measured while vaping, and their puffing behavior was tracked over 10 days. The goal was to unders…
Matched conditions: TOBACCO DEPENDENCE
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Could Low-Nicotine smokes plus E-Cigs cut harm for mentally ill smokers?
Knowledge-focused CompletedThis study looked at whether using very low nicotine cigarettes along with nicotine-containing e-cigarettes can reduce harmful chemical exposure in smokers with mental health conditions. 88 participants were assigned to different combinations of cigarettes and e-cigarettes. The m…
Matched conditions: TOBACCO DEPENDENCE
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:59 UTC