THERMAL BURN
Clinical trials for THERMAL BURN explained in plain language.
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Can plasma given right away save more burn victims?
Disease control Not yet recruitingThis study tests whether giving plasma (a part of blood) as soon as possible to adults with severe burns over at least 20% of their body can lower the chance of death or organ failure. About 750 patients will be randomly assigned to receive either early plasma or standard fluids.…
Matched conditions: THERMAL BURN
Phase: PHASE3 • Sponsor: Jason Sperry • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Can a common antidepressant cream stop Burn-Induced cellular 'Debris'?
Knowledge-focused Not yet recruitingThis study investigates whether a topical cream containing amitriptyline, a drug typically used for depression and pain, can block the release of microvesicle particles (MVPs) from skin after a small thermal burn. Healthy adults aged 18-64 receive a tiny, controlled burn on their…
Matched conditions: THERMAL BURN
Phase: PHASE1 • Sponsor: Wright State University • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Can a common antidepressant calm burn damage? early study investigates
Knowledge-focused Not yet recruitingThis pilot study tests whether a single 75mg dose of amitriptyline can reduce the release of microvesicle particles (tiny substances) from skin after a very small, controlled burn. Twenty healthy adults will receive either amitriptyline or a placebo, then a small heated rod creat…
Matched conditions: THERMAL BURN
Phase: PHASE1 • Sponsor: Wright State University • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC