TETANUS

This first-in-human study tests a new microneedle patch (Miracus) that dissolves in the skin to deliver a tetanus vaccine without a needle. Thirty healthy adults will receive either an empty patch or one loaded with vaccine. Researchers will check safety, tolerability, and whethe…

This study tests a new vaccine called TdaP2gen in 320 pregnant women in Thailand to see if it safely protects their babies from tetanus, diphtheria, and whooping cough. The vaccine is given during pregnancy, and researchers measure antibody levels in mothers and infants up to 18 …

This early-stage trial is testing a new tetanus vaccine in 80 adults aged 18 and older. The study is randomized and double-blind, meaning neither participants nor doctors know who gets the new vaccine versus an existing one. The main goal is to check for side effects within the f…

This early-stage trial is testing a new combination vaccine that protects against whooping cough, diphtheria, and tetanus (Tdap) in people aged 10 and older. Researchers want to see if different doses are safe and trigger an immune response. The study involves 96 volunteers and c…

This study tests a new version of the Tdap vaccine (which protects against tetanus, diphtheria, and whooping cough) that has reduced antigens. The goal is to see if it is safe and triggers a strong immune response in people aged 6 and up. Around 660 volunteers will receive either…

This study aims to create a quick, non-invasive test using saliva to see if someone has enough antibodies to fight tetanus. Instead of drawing blood, a small saliva sample on a test strip would give results in 10-15 minutes. The test is designed for low- and middle-income areas w…

This study tests a new medicine called SNA02-48 to see if it can prevent tetanus in people who have had a high-risk wound, like a deep cut or puncture from a dirty object. About 600 adults will receive either the new injection or the standard treatment (human tetanus immunoglobul…

This study tests a new medicine called siltartoxatug to prevent tetanus in people who have been injured. About 6,000 adults in China will receive either the new drug or a standard tetanus shot. Researchers will check how well each treatment prevents tetanus over 90 days and monit…