TARGETED THERAPY
Clinical trials for TARGETED THERAPY explained in plain language.
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New combo therapy aims to shrink rectal tumors before surgery
Disease control Recruiting nowThis study tests whether adding an immunotherapy drug (PD-1 inhibitor) to a standard treatment plan (short-course radiation, chemotherapy, and a targeted therapy) can improve outcomes for people with locally advanced rectal cancer. About 104 participants will receive the standard…
Matched conditions: TARGETED THERAPY
Phase: PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated May 16, 2026 23:51 UTC
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New hope for esophageal cancer: combining immunotherapy with standard treatment
Disease control Recruiting nowThis study looks at whether adding immunotherapy or targeted drugs to standard chemoradiotherapy can help people with esophageal or esophagogastric junction cancer live longer. It involves 2,000 adults with stage I to IVa cancer who are not able to have surgery. The goal is to fi…
Matched conditions: TARGETED THERAPY
Phase: PHASE3 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated May 16, 2026 23:38 UTC
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New combo therapy targets tough blood cancers
Disease control Recruiting nowThis study is for adults with blood cancers that have returned or not responded to treatment and have specific gene changes (IDH1 and another signaling mutation). The purpose is to see if combining the drug olutasidenib with other targeted therapies is safe and tolerable. About 6…
Matched conditions: TARGETED THERAPY
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Could Low-Dose radiation boost cancer treatment before surgery?
Disease control Recruiting nowThis study is for people with operable head and neck squamous cell carcinoma. It compares two treatment approaches given before surgery: one combines low-dose radiotherapy with targeted therapy and immunotherapy, the other uses only targeted therapy and immunotherapy. The goal is…
Matched conditions: TARGETED THERAPY
Phase: PHASE2 • Sponsor: West China Hospital • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New combo therapy targets hard-to-treat liver metastases in colorectal cancer
Disease control Recruiting nowThis study tests a combination of two drugs (fruquintinib and sintilimab) with or without radiation therapy for people with colorectal cancer that has spread to the liver and hasn't responded to two prior treatments. The goal is to see if this approach can control the cancer long…
Matched conditions: TARGETED THERAPY
Phase: PHASE2 • Sponsor: Shandong Cancer Hospital and Institute • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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New hope for esophageal cancer: study tests best Pre-Surgery combo
Disease control Recruiting nowThis study aims to find the best treatment before surgery for esophageal cancer. It compares chemotherapy, chemoradiation, targeted therapy, and immunotherapy in 2000 adults with stage I-IVa disease. The goal is to improve survival and reduce side effects.
Matched conditions: TARGETED THERAPY
Phase: PHASE3 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated May 07, 2026 18:43 UTC
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New program aims to ease emotional burden of advanced lung cancer
Symptom relief Recruiting nowThis study is testing a new supportive care program called POISE for people with advanced non-small cell lung cancer. The program includes four visits with a specially trained palliative care clinician to help patients cope with uncertainty and manage their cancer journey. Resear…
Matched conditions: TARGETED THERAPY
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 16, 2026 23:48 UTC
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Healthy volunteers first to test experimental exosome drug SOB100
Knowledge-focused Recruiting nowThis early-stage study tests a new drug called SOB100, which uses tiny particles called exosomes to target a protein named HLA-G. The goal is to see if it is safe and how the body processes it in 15 healthy adults. No treatment is given — this is purely a safety and dosing study.…
Matched conditions: TARGETED THERAPY
Phase: PHASE1 • Sponsor: Shine-On Biomedical Co., Ltd. • Aim: Knowledge-focused
Last updated May 16, 2026 23:51 UTC
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Your mood may impact liver cancer therapy success
Knowledge-focused Recruiting nowThis study looks at whether a patient's emotional state—like depression or anxiety—can influence how well advanced liver cancer responds to a combination of chemotherapy, targeted therapy, and immunotherapy. Researchers will follow 90 adults with BCLC stage B or C liver cancer, d…
Matched conditions: TARGETED THERAPY
Sponsor: Nanfang Hospital, Southern Medical University • Aim: Knowledge-focused
Last updated May 16, 2026 23:47 UTC