SUICIDE, ATTEMPTED

This trial tests a therapy called SAFETY, designed to help teenagers who have recently attempted suicide. The study will include 282 youths aged 10-17 and their caregivers. Half will receive SAFETY, a family-based cognitive-behavioral program, and the other half will get enhanced…

This study tests whether adding a crisis response plan (CRP) to prolonged exposure (PE) therapy helps reduce suicidal thoughts and behaviors in people with PTSD. Researchers will compare PE plus CRP to PE with standard care in 100 adults. The goal is to find a better way to suppo…

This study tests a new therapy called Written Exposure Therapy for Suicide Prevention (WET-SP) in 160 active duty military members hospitalized for suicidal thoughts or attempts. Participants either receive the therapy plus standard care, or standard care alone. The therapy invol…

This study is testing a structured program called SHIELD to help young people aged 15-30 who have suicidal thoughts or self-harm. The program includes 8 weekly sessions tailored by age, focusing on stabilizing daily routines and emotions. Researchers will compare it to usual care…

This study aims to find the best way to prevent suicide in young people ages 12-24 who are at high risk. Researchers will compare two short, proven crisis interventions given in emergency rooms: one focuses on creating a safety plan and follow-up calls, while the other teaches sk…

This study tests whether ketamine, given as an IV infusion, can quickly lower severe suicide risk in young people aged 14 to 30 who have just attempted suicide. Participants receive either ketamine or a placebo while in the hospital, plus weekly therapy sessions. The goal is to s…

This study is testing a type of talk therapy, called Brief Cognitive Behavioral Therapy for Suicide Prevention, delivered via video call. The goal is to see if it can reduce suicidal thoughts and attempts in adults with physical disabilities affecting vision, hearing, or mobility…

This study tests a program called TAILOR, which uses sleep-focused therapy to help teens with insomnia who are also having suicidal thoughts. The goal is to see if improving sleep can lower their risk of suicidal behavior. The study will enroll 235 teens aged 11-18 and track chan…

This study tests a 40-minute web-based program designed to teach veterans coping skills for suicidal thoughts. Researchers will compare veterans who use the program to those receiving standard care, measuring changes in suicidal thoughts and behaviors over one month. The goal is …

This study tests a new short-term treatment called Suicidal Crisis Intervention (SCI) for adults who have attempted suicide or are in a suicidal crisis. The goal is to reduce suicidal thoughts and related feelings like hopelessness. About 390 participants will be randomly assigne…

This study tests a mobile app called WellPATH-PREVENT for adults aged 50-90 who were recently hospitalized for suicidal thoughts or a suicide attempt. The app teaches emotion regulation skills to help reduce suicide risk. Researchers will measure changes in brain activity, self-r…

This study is testing a program called STEP that teaches teens skills like mindfulness, gratitude, and savoring positive moments. The goal is to see if it can reduce suicidal thoughts and attempts after a teen is discharged from inpatient psychiatric care. 216 teens will be rando…

This study tests whether a virtual reality (VR) training program can help healthcare providers better counsel rural veterans about suicide prevention and safe storage of firearms and medications. Thirty-six providers will be randomly assigned to either the VR training or a standa…

This study tests whether giving emergency room doctors a computer-generated risk score for suicide can help prevent suicide attempts. About 4,000 adults coming to the ER for psychiatric issues will be randomly assigned so that their doctor either sees or does not see their risk s…

This study is for adults with depression who have recently attempted suicide. It tests a group program that teaches emotion regulation and values to improve daily functioning and prevent future suicide attempts. Researchers will also measure thinking skills, quality of life, and …

This study follows 415 people with difficult-to-treat depression for 5 years after they joined an earlier genetics study. Researchers will review medical records and registry data to see how patients' depression changes over time, including suicide attempts and treatment response…

This study tests if an electronic program that teaches healthy coping and problem-solving skills can reduce suicide risk in teens who have recently attempted suicide. Researchers will compare teens who use the program to those who receive standard care. The goal is to see if the …

This study looks at how a brief therapy program called ASSIP affects thinking and behavior in adults who have attempted suicide. Participants are randomly assigned to receive ASSIP or standard care plus a resource interview. Researchers measure changes in impulse control and othe…

This study looks at how the brain works in people who have attempted suicide compared to those who have only thought about it. Researchers will use simple computer tasks to measure things like impulse control and attention. The goal is to find patterns that might help predict who…