STOMACH CANCER

This study tests a new robotic system with an extra arm for stomach cancer surgery. Ten adults with stomach cancer will have their surgery using this robot. The goal is to see if the robot is safe and can complete the surgery without switching to other methods.

This study tests two drugs, avutometinib and defactinib, given together to people with a specific, hard-to-treat type of stomach cancer that has spread. The goal is to see if the combination can shrink tumors and help people live longer. About 27 adults who have already tried at …

This study tests a new drug called ivonescimab combined with standard chemotherapy (FOLFOX) in people with advanced HER2-negative stomach or esophagus cancer that has not been treated before. The goal is to see if the combination can keep the cancer from growing for at least 6 mo…

This early-phase trial tests a new drug (CA-4948) combined with standard chemotherapy and immunotherapy for people with advanced stomach, esophageal, or gastroesophageal junction cancer that cannot be removed by surgery. The study includes two groups: one for HER2-negative cancer…

This study tests a new drug called 3H-10000 in people with advanced lung or stomach cancer that cannot be removed by surgery or has spread. The drug is designed to target and kill cancer cells while limiting harm to healthy cells. The trial aims to find the safest dose and see if…

This early-phase study tests a new treatment called PTC13, which uses specially engineered immune cells (CAR-T cells) to attack cancer cells that have a protein called CEA. The study includes 18 adults with advanced colorectal, stomach, pancreatic, or other solid tumors that have…

This study is testing a new blood test that looks for DNA signals from 20 different cancers, including lung, breast, and colon cancer. Researchers will enroll 7,000 people to see if the test can find cancer early, detect any cancer left after treatment, and spot a relapse before …

This study is testing a new type of PET scan that uses special probes to highlight digestive system cancers, such as stomach, liver, colon, and pancreatic cancers. Researchers will enroll 400 adults to see how well this imaging method finds tumors and tracks their response to tre…

This study looks at whether the things people buy at stores—like pain relievers or digestive aids—could be early warning signs of cancer. Researchers will compare the shopping habits of 2900 people, some diagnosed with cancer and some not, to see if certain purchases happen more …

This study is testing whether squeezing a stress ball during chemotherapy can help reduce nausea, anxiety, and fatigue in people with stomach cancer. About 52 adults will take part. Researchers will measure their symptoms during treatment to see if this simple, drug-free tool mak…

This study tests whether using virtual reality (VR) can reduce severe belly pain and improve quality of life in people with digestive tract cancers. 360 participants will be split into three groups: one using a skills-based VR program, one using distracting VR videos, and a contr…

This study tests whether brodalumab, a drug used for autoimmune diseases, can safely reduce side effects caused by cancer immunotherapy. About 11 adults with various cancers who have developed immune-related side effects will receive brodalumab. The goal is to see if it can lower…

This study focuses on improving the quality of care for Black patients newly diagnosed with gastrointestinal cancer. It helps ensure patients get the right biomarker tests, offers assistance in joining other clinical trials, and provides educational materials to improve understan…

This study tests whether a large language model (AI) can help junior doctors write more accurate and efficient cancer treatment reports. Forty doctors will be split into two groups: one using AI assistance, the other using traditional methods. The reports will be scored by expert…

This study collects tissue and blood samples from people with stomach or esophageal cancer, as well as those at high inherited risk, to learn how genes and proteins contribute to these cancers. The goal is to better understand the disease, not to test a new treatment. About 100 p…