STEMI
Clinical trials for STEMI explained in plain language.
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Diabetes drug could shield heart muscle during angioplasty
Disease control OngoingThis phase 2 trial tests whether empagliflozin (Jardiance), a diabetes drug, can reduce the 'no-reflow' phenomenon—when blood flow fails to fully restore after angioplasty—in 162 heart attack patients. Participants receive a loading dose before the procedure and daily doses for 3…
Matched conditions: STEMI
Phase: PHASE2 • Sponsor: Instituto Nacional de Cardiologia Ignacio Chavez • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Experimental antibody aims to shield hearts after stent treatment
Disease control OngoingThis early-stage study tests a monoclonal antibody called atibuclimab (IC14) in 10 adults who had a severe heart attack (STEMI) and received a stent. The drug is given by IV to see if it can prevent further heart muscle damage and reduce inflammation. Participants are compared to…
Matched conditions: STEMI
Phase: PHASE1, PHASE2 • Sponsor: Implicit Bioscience • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Heart clot showdown: new blood thinner vs. old standard in major trial
Disease control OngoingThis study tests whether a newer type of blood thinner (DOA) works better than the standard one (VKA) for dissolving dangerous blood clots inside the heart. About 340 adults with such clots will be randomly assigned to one of the two treatments. The goal is to see which drug redu…
Matched conditions: STEMI
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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AI reads your Heart's electrical signals to find hidden blockages
Diagnosis OngoingThis study enrolls 800 patients having heart attacks to test an artificial intelligence model that reads standard 12-lead ECGs. The AI aims to detect which artery is blocked and how severely blood flow is reduced, at the moment of a heart catheterization. If accurate, this could …
Matched conditions: STEMI
Sponsor: Powerful Medical • Aim: Diagnosis
Last updated Jun 27, 2026 11:03 UTC
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Can better Decision-Making save heart attack victims in shock?
Knowledge-focused OngoingThis study looks at how doctors treat people having a severe heart attack complicated by cardiogenic shock, where the heart can't pump enough blood. Researchers will track 124 patients at 20 U.S. hospitals to see how decisions about using mechanical heart support devices affect s…
Matched conditions: STEMI
Sponsor: Henry Ford Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC