STAGE IV HEPATOCELLULAR CARCINOMA AJCC V8
Clinical trials for STAGE IV HEPATOCELLULAR CARCINOMA AJCC V8 explained in plain language.
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Engineered immune cells take on tough liver cancer in early trial
Disease control TerminatedThis early-phase study tests a new treatment for adults with advanced liver cancer that has not responded to at least two standard therapies. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack cancer cells that have a specific p…
Matched conditions: STAGE IV HEPATOCELLULAR CARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Tailored radiation doses aim to shrink liver tumors
Disease control OngoingThis study tests whether giving a personalized dose of radiation directly to liver tumors can improve treatment results for people with advanced liver cancer that cannot be removed by surgery. About 42 participants will receive a customized radiation plan based on their individua…
Matched conditions: STAGE IV HEPATOCELLULAR CARCINOMA AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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New combo therapy shows promise for HIV patients with advanced cancer
Disease control OngoingThis early-phase trial is testing the safety of combining two cancer drugs—nivolumab and cabozantinib—in people with HIV who have advanced solid tumors. The study includes 8 participants with various cancers that have spread. The goal is to see if the combination can shrink or st…
Matched conditions: STAGE IV HEPATOCELLULAR CARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Immunotherapy duo after radiation shows promise for inoperable liver cancer
Disease control OngoingThis early-phase study tests whether giving two immunotherapy drugs (durvalumab and tremelimumab) after a targeted radiation procedure can help people with advanced liver cancer that cannot be surgically removed. The trial includes 25 adults whose cancer has spread within the liv…
Matched conditions: STAGE IV HEPATOCELLULAR CARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 07, 2026 18:43 UTC
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New combo shows promise for Tough-to-Treat bile duct cancer
Disease control OngoingThis study tests a new drug called pevonedistat, given alone or with standard chemotherapy (paclitaxel and carboplatin), in people with advanced bile duct cancer that has spread or cannot be removed. The goal is to see if the combination can shrink tumors. About 40 adults who hav…
Matched conditions: STAGE IV HEPATOCELLULAR CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 24, 2026 16:05 UTC