New drug combo aims to boost immune attack on tough liver cancers

NCT ID NCT03655002

First seen May 16, 2026 ยท Last updated May 16, 2026

Summary

This early-phase trial tested a combination of two drugs (IRX-2 and nivolumab) plus a low dose of chemotherapy in 8 adults with advanced liver cancer that had returned or spread. The goal was to find the best dose and check for side effects. The approach aims to help the immune system fight the cancer more effectively.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • HonorHealth Research Institute

    Scottsdale, Arizona, 85258, United States

  • Texas Oncology at Baylor Charles A Sammons Cancer Center

    Dallas, Texas, 75246, United States

Conditions

Explore the condition pages connected to this study.