Tailored radiation beams aim to boost liver cancer treatment

NCT ID NCT03896646

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests whether giving liver cancer patients a personalized dose of radiation (Yttrium-90) can improve tumor shrinkage compared to standard dosing. The study includes 42 adults with advanced liver cancer that cannot be removed by surgery. Researchers use special scans to tailor the radiation dose to each patient's tumor and liver function, aiming to maximize effectiveness while minimizing harm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Yttrium-90 radioembolization with personalized dosimetry

What this could lead to

If successful, this could make radiation therapy more effective for liver cancer patients who cannot have surgery, potentially improving tumor shrinkage and survival.

What could go wrong

This is a small, early-phase trial with only 42 participants, so results may not apply to everyone. Personalized dosing may not improve outcomes and could still cause liver damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States