STAGE IIIA NON-SMALL CELL LUNG CANCER
Clinical trials for STAGE IIIA NON-SMALL CELL LUNG CANCER explained in plain language.
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New drug duo tested in fight against tough cancers
Disease control CompletedThis study tested whether combining an experimental drug (sEphB4-HSA) with an approved immunotherapy (pembrolizumab) could help control advanced lung or head/neck cancers that had worsened after standard chemotherapy. It involved 42 patients who received both drugs by IV infusion…
Matched conditions: STAGE IIIA NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Vaccine-Immunotherapy combo tested in Tough-to-Treat lung cancer
Disease control CompletedThis study tested whether combining a cancer vaccine (TG4010) with an immunotherapy drug (nivolumab) could help control advanced non-small cell lung cancer in patients whose previous treatments had stopped working. The vaccine aims to train the immune system to recognize and atta…
Matched conditions: STAGE IIIA NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: Megan Daly, MD • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New drug combo tested for Tough-to-Treat lung cancers
Disease control CompletedThis early-stage trial tested a combination of two existing drugs, auranofin and sirolimus, for patients with advanced or returning lung cancer who had no other standard treatments left. The main goals were to find the safest dose and see if the drugs could slow the cancer's grow…
Matched conditions: STAGE IIIA NON-SMALL CELL LUNG CANCER
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Early trial tests adding immunotherapy to standard lung cancer care
Disease control CompletedThis early-stage study tested the safety of adding a newer immunotherapy drug (pembrolizumab) to the standard treatment of chemotherapy and radiation for patients with inoperable, locally advanced non-small cell lung cancer. The main goal was to find the safest dose and understan…
Matched conditions: STAGE IIIA NON-SMALL CELL LUNG CANCER
Phase: PHASE1 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Diabetes drug added to lung cancer treatment in groundbreaking trial
Disease control CompletedThis study tested whether adding the common diabetes medication metformin to standard chemotherapy and radiation could better control stage III non-small cell lung cancer. Researchers randomly assigned 170 patients with inoperable lung cancer to receive either the standard treatm…
Matched conditions: STAGE IIIA NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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MRI-Guided radiation trial aims to control tough lung cancers
Disease control CompletedThis study tested whether using MRI guidance could make radiation treatment more precise for people with inoperable, advanced non-small cell lung cancer. Twenty-six participants received a combination of targeted radiation, chemotherapy, and an immunotherapy drug called durvaluma…
Matched conditions: STAGE IIIA NON-SMALL CELL LUNG CANCER
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Mar 12, 2026 13:52 UTC